ALNYLAM PHARMACEUTICALS INC

NATERA INC

NEUROCRINE BIOSCIENCES INC

INSMED INC

UNITED THERAPEUTICS CORP

IOVANCE BIOTHERAPEUTICS INC

VERTEX PHARMACEUTICALS INC

CYTOKINETICS INC

BIOGEN INC

EXACT SCIENCES CORP

SPDR Series Trust - State Street SPDR S&P Biotech ETF is an exchange traded fund launched by State Street Global Advisors, Inc. The fund is managed by SSGA Funds Management, Inc. It invests in public equity markets of the United States. It invests in stocks of companies operating across health care, pharmaceuticals, biotechnology and life sciences sectors. The fund invests in growth and value stocks of companies across diversified market capitalization. It seeks to track the performance of the S&P Biotechnology Select Industry Index, by using representative sampling technique. SPDR Series Trust - State Street SPDR S&P Biotech ETF was formed on January 31, 2006 and is domiciled in the United States.

State Street SPDR S&P Biotech ETF

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